Acknowledgement:

This project has received funding from the European Union´s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No. 813294 (ENTRAIN).

2023

Neural cortical organoids from self-assembling human iPSC as a model to investigate neurotoxicity in brain ischemia, Journal of Cerebral Blood Flow & Metabolism, 18 Jan 2023, doi: 10.1177/0271678X231152023

2022

Can We Treat Neurodegenerative Proteinopathies by Enhancing Protein Degradation?, Movement Disorders, 17 May 2022, Vol 37, No. 7, pp. 1346-1359, doi: 10.1002/mds.29058 

Specification of CNS macrophage subsets occurs postnatally in defined niches, Nature, 20 Apr 2022, Vol 604, pp. 740-748, doi: 10.1038/s41586-022-04596-2

tPA-NMDAR Signaling Blockade Reduces the Incidence of Intracerebral Aneurysms, Transl. Stroke Res. ISSN, 21 Mar 2022, Vol 13, pp.1005-1016, doi: 10.1007/s12975-022-01004-9

Microglia modulate blood flow, neurovascular coupling, and hypoperfusion via purinergic actions, J. Exp. Med., 24 Feb 2022, Vol 219, No 3, doi: 10.1084/jem.20211017

2021

Modeling ischemic stroke in a triculture neurovascular unit on-a-chip, Fluids and Barriers of the CNS, 14 Dec 2021, 18, 59. doi: 10.1186/s12987-021-00294-9

Formation of a protein corona on the surface of extracellular vesicles in blood plasma, Jour. Extracell. Ves., 14. Sep 2021, Vol 10, Issue 11

Alpha-Synuclein in the Regulation of Brain Endothelial and Perivascular Cells: Gaps and Future Perspectives, Frontiers in Immunology, 19 Feb 2021, Vol. 12, 611761. doi: 10.3389/fimmu.2021.611761

2020

Endogenous THBD (Thrombomodulin) Mediates Angiogenesis in the Ischemic Brain
 Arterioscler Thromb Vasc Biol. 2020 Oct 8;ATVBAHA120315061. doi: 10.1161/ATVBAHA.120.315061. 

Surfaceome dynamics reveal proteostasis-independent reorganization of neuronal surface proteins during development and synaptic plasticity, Nat Commun. 2020 Oct 5;11(1):4990. doi: 10.1038/s41467-020-18494-6.

Filling the gaps on stroke research: Focus on inflammation and immunity, Brain Behav Immun. 2020 Oct 2 doi: 10.1016/j.bbi.2020.09.025 [Epub ahead of print]

Alcohol exposure-induced neurovascular inflammatory priming impacts ischemic stroke and is linked with brain perivascular macrophages. M. JCI Insight. 2020 Feb 27;5(4):e129226. doi: 10.1172/jci.insight.129226

Hyperinsulinemia promotes endothelial inflammation via increased expression and release of Angiopoietin-2, J. Atherosclerosis, 2020 Aug 2020, 307(1-10). doi:10.1016/j.artheriosclerosis.2020.06.016

Microglia monitor and protect neuronal function through specialized somatic purinergic junctions, Science, 31 Jan 2020, Vol. 367, Issue 6477, pp. 528-537, doi: 10.1126/science.aax6752

Dendritic Cells and Microglia Have Non-redundant Functions in the Inflamed Brain with Protective Effects of Type 1 cDCs, Cell Reports, 20 Oct 2020, Vol. 33, Issue 3; doi: 10.1016/j.celrep.2020.108291

Generation of a human induced pluripotent stem cell line (UEFi003-A) carrying heterozygous A673T variant in amyloid precursor protein associated with a reduced risk of Alzheimer’s disease, Stem Cell Research, Oct 2020, Vol.48, 1019668; doi: 10.1016/j.scr.2020.101968

2019

Plasminogen Activator Inhibitor-1 (PAI-1) deficiency predisposes to depression and resistance to treatments, Acta Neuropathologica Communications, 14 Oct 2019, Vol. 7, Art. 153, doi:10.1186/s40478-019-0807-2